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ALC is considered safe when taken in accordance with the instructions on the product dietary panel

However, the weight loss effects observed in patients taking GLP-1 agonists for diabetes have led to an increase in off-label prescribing for obesity and weight management in individuals without diabetes

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The use of an 8.0% (64 mmol/mol) HbA1c treatment intensification threshold in the base case analysis was a deviation from previously published long-term analyses of oral semaglutide, which used a 7.5% (58 mmol/mol) threshold [16, 26, 27]

Garg Arun

Data availability The authors declare that all data supporting the findings of this study are available in the Methods and Supplementary data of this article