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In metabolic disorders such as T2D and obesity, a dysbiotic, low-SCFA microbiome, often characterized by a higher Bacillota-to-Bacteroidota ratio and a depletion of Akkermansia muciniphila, is associated with impaired baseline incretin secretion, contributing to insulin resistance (6972)

ALCAR has been utilized in clinical settingsparticularly in Europesince the 1980s, primarily for addressing age-related cognitive deficits and peripheral neuropathies

457 The production of iron-dependent hydroxyl radicals has been associated with muscle necrosis in a mouse model of DMD, and iron deprivation can decrease muscle necrosis and has potential therapeutic benefits

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Ong S, Ming L, Lee K, Yuen K

Arner, P