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Some slight bruising, redness, or inflammation around the injection site can occur

The lack of diversity across trials that are modeling disease progression or assessing the efficacy of interventions can result in biased or inaccurate findings that have low external validity, or generalizability, and can further exacerbate existing disparities in AD/ADRD health outcomes

Figure 5: Changes in the body weight and body length of both male and female KID, KIR, and control mice

The weekly injections are designed to be convenient, allowing patients to incorporate the treatment into their routine with minimal disruption

Intranasal administration offers good bioavailability (60-70%) with improved patient compliance