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In this same study, the anorexic effect of microinjection of Ex4 into the VTA was reduced by an AMPA/kainate antagonist and Ex4 increased AMPA/kainate receptor-mediated sEPSC frequency in VTA dopaminergic neurons

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2 Study Flow Diagram for Selecting Patients Initiating Glucagon-Like Peptide-1 Receptor Agonist (GLP-1RA) or Sodium-Glucose Cotransporter-2 Inhibitor (SGLT-2i)