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Julie E H, Neil W, Jeffrey S, Eileen C, Nehal G, Ryan M et al

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The morphological changes that occur are due to decreased mitochondrial volume, increased lipid bilayer membrane density and the decrease or disappearance of mitochondria (28)

In agreement with observed resistance in KO mice, levels of phosphorylated AMPK subunit (at Thr172 residue) were higher in the livers of KO mice than in WT mice in all diet groups (Fig