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reported mass can depend on the supplied molecular form

( Unfortunately, this symptom of B12 deficiency overlaps with symptoms related to diabetic neuropathy nerve damage caused by high blood sugar that can cause pain and numbness in the extremities ( People with diabetes taking metformin are at a higher risk of developing B12 deficiency because this medication can reduce vitamin B12 absorption in the body ( So, a B12 deficiency could be misdiagnosed as peripheral neuropathy in people with diabetes

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Mass spectrometry (MS) confirmation: The COA should confirm the observed mass matches the expected molecular weight of 850.9 g/mol (or the protonated [M+H]+ ion at 851.9 for electrospray ionization MS)

Resources and Costs To estimate the resources needed to switch all patients from vitamin B12 intramuscular injections to high-dose oral B12 supplements, physician experts were consulted

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