The clinical correlate is an infarct (stroke, myocardial infarction)
ROS accumulation in GCs disrupts mitochondrial apoptosis and reduces the expression of several transcription factors, such as GDF9 and BMP15 , which are crucial for oocyte competence
Damian Holsinger, The University of Sydney, Australia Reviewed by Muhammad Usman Munir, Jouf University, Saudi Arabia Omamuyovwi Meashack Ijomone, University of Medical Sciences, Ondo, Nigeria Updates Copyright 2025 Yassin, Skrabulyte-Barbulescu, Alshamsi, Saeed, Alkuwaiti, Almazrouei, Alnuaimi, BaniYas, Aldhaheri, Alderei, Shehab and Hamad
The study, published in Nature , shows that tumors can break down glutathione to support their growth, challenging long-held assumptions about its role in human health
Doses were inconsistent, side effects showed up more often than expected, and in some cases, the risks were serious enough to outweigh any potential benefits
352 Therefore, intravitreal injection of corticosteroid is an option for patients who are not candidates for anti-VEGF therapy