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2006 The FDA mandated that J&J add a warning about serious eye disorders, such as acute myopia and secondary angle-closure glaucoma, which can lead to permanent visual loss

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Others report that previously stable hair loss worsened during therapy

At present, studies have confirmed that ferroptosis occurs in neuronal cells during the onset of stroke, ferroptosis mediates the pathophysiological process of stroke, and inhibition of ferroptosis has a protective effect on stroke, which can improve stroke prognosis [106]