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Interestingly, NP (0.1100 M) increased LNCaP viability and migration similarly to DHT (10 nM), an effect reversed by the AR antagonist Casodex, suggesting that NP can indeed act via the AR signalling pathway [286]

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They showed that pravastatin inhibited tumor metastasis to the lung by reducing liver matrix metalloproteinase-9 (MMP-9) activity and suppression of MMP2, which was mainly attributed to down-regulation of MMP-14 in hepatocellular carcinoma [99]