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Reduction or loss of SOD2 expression was thought to affect the progression of the cell cycle by increasing oxidant-mediated DNA damage

The conversion of homocysteine to methionine reduces the potential for damage because the reaction results in the formation of the super-antioxidant glutathione

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Some examples include: NADPH quinone dehydrogenase (NQO1), heme oxygenase 1 (HO1), the two subunits of glutamate-cysteine ligase (GCL), glutamate-cysteine ligase modifier (GCLM, the rate-limiting enzyme for GSH synthesis), SOD 1, CAT, sulfiredoxin, thioredoxin, and peroxiredoxin [68, 137, 162, 163]

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Alzheimers disease: Molecular aspects and treatment opportunities using herbal drugs