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Thus the improvement associated with folic acid supplementation and lower Hcy levels can be most directly explained by an improvement in MS activity and D4 dopamine receptor-mediated PLM [46]

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Over 99% of circulating thyroid hormones bind to plasma proteins such as thyroxine-binding globulin (TBG), thyroxine-binding prealbumin (TBPA), and albumin, contributing to T4s longer half-life compared to T3