PMC12193160 Bissett, D
Critically, AOD-9604 did not produce the metabolic side effects associated with full-length growth hormone, including no insulin resistance or glucose intolerance, no elevation of IGF-1 levels, no fluid retention or joint pain, and no cardiovascular parameter changes
The subjects here exhibited relatively little cognitive deficit or mitochondrial dysfunction in the hippocampus, and their cognitive function was comparable to that of the control group that did not receive isoflurane.8 Alzheimers disease Mitochondrial dysfunction appears to be a central event in the pathogenesis of Alzheimers disease, so the preservation of mitochondrial health may be one of the keys to disease prevention.9 To that end, a 2017 study points favorably to SS-31s use for Alzheimers prevention
Prescribers should document their clinical rationale, including the absence of contraindications, in the patient's medical record
Gastroenterology 129 , 591608 (2005)
[2] Sigalos JT, Pastuszak AW, Allison A, et al