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Key Takeaway: Titration is a safety-first approach designed to help your body build tolerance to semaglutide while minimizing gastrointestinal side effects

In some, as the disease progresses, despite titration of the basal insulin to correct fasting hyperglycaemia (typically more than 0.5 U/kg), mealtime insulin may have to be added to meet glycaemic targets, particularly postprandial glucose [328]