[Google Scholar] 221.Bodles AM, Banga A, Rasouli N, Ono F, Kern PA, Owens RJ
My endometriosis pain has been noticeably better too
Flags theoretical pathologic angiogenesis potential: PMC12446177 Evidence Summary Preclinical: IBD/colitis models: High remission rates, restored mucosal architecture, improved barrier function Tendon repair: Accelerated healing, improved tensile strength, reduced fibrosis Neurovascular: Sciatic nerve protection, enhanced blood vessel growth in nerve tissue Human data (emerging): Interstitial cystitis pilot (2024, n=12): 10/12 complete resolution, 2/12 at 80% improvement IV safety study (2025, n=2): no adverse effects on cardiac, hepatic, renal, or glucose biomarkers Knee pain retrospective (2021, n=17): 91.6% reported significant improvement No large-scale controlled trials published Safety: No immunosuppression or hormonal disruption in available data 2025 systematic review (HSS Journal): recommends caution due to limited high-quality clinical evidence 2025 narrative review: flags theoretical pathologic angiogenesis risk Stable in gastric acid (oral administration viable) No observed toxicity at therapeutic doses in published reports Foundational Reviews Sikiric P, Seiwerth S, et al
Direct Delivery: Prescriptions are fulfilled by licensed, FDA-regulated U.S
Another study revealed that patients with MASLD face 3.8 times higher odds of lifetime depression compared to those without liver disease
Clarifying the specific interactions and signaling pathways that control antioxidant enzymes should be a primary goal of future studies
