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GLP-1RAs reduce inflammation, systemic endothelial function, and modestly improve cerebral perfusion, particularly in individuals with insulin resistance, obesity, or metabolic syndrome [15]

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[PMC free article: PMC3949112] [PubMed: 24477539] 183

A recent investigation by 5 Molecular pathways of neuroprotection The principal molecular pathways involved in semaglutide-mediated neuroprotection are shown in Figure 2