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Even with the oral administration of an extremely high dose (3 g) of glutathione, it was not possible to achieve any changes in the amount of the substance circulating in the blood

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South Med J 98(2):235237

Results vary based on several factors: Your starting point: Those with higher levels of oxidative stress may notice changes faster

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A patient in their 30s with no metabolic issues and a clean training history will respond differently than a patient in their 50s with insulin resistance and 80 extra pounds