According to the NICE Clinical Knowledge Summary (CKS) and the British National Formulary (BNF) , the standard treatment for B12 deficiency without neurological symptoms involves: Hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks Followed by maintenance doses of 1 mg every three months For patients with neurological symptoms (such as paraesthesia, numbness, cognitive changes, or gait disturbances), more intensive treatment is required: Hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement occurs Followed by 1 mg every two months for maintenance Pernicious anaemia , an autoimmune condition where the body cannot produce intrinsic factor, requires lifelong treatment
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Mental and emotional factors like stress, anxiety, and depression can also affect the release of stomach acid needed to digest protein (which ensures that B12 is released from your food), says Kozlowski
By supporting red blood cell production, nerve function, and cellular energy processes, B12 injections may help improve feelings of fatigue, low energy, and overall wellness
Additionally, B12 is essential for maintaining healthy nerve cells and supporting neurological function, which can positively impact your mood, mental clarity, and cognitive health
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