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Insulin-like growth factor-1, as discussed earlier, has implications on lipid and glucose metabolism [87, 88], and its exogenous administration enhances insulin sensitivity in healthy adults [139, 140] as well as those with T2D [155]

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Tumor necrosis factor- is highly related to muscle wasting conditions such as cancer cachexia as well as AIDS and other muscle inflammatory conditions

General Eligibility Criteria BMI over 30: Individuals categorized as having obesity