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First, nanocarriers directly deliver ferroptosis modulators to molecular targets, depleting GSH via cystine disruption, inhibiting GPX4, or elevating labile iron pools to amplify lipid peroxidation

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[12] Orlistat: A lipase inhibitor available on NHS prescription (120 mg) or over the counter (60 mg, branded as Alli)

Direct SlC7A11 overexpression in cardiac myocytes boosted GSH levels and reduced cardiac ferroptosis and injury, suggesting that it is feasible to fortify GSH levels by increasing SLC7A11 [76]

What patients do report, typically transiently, includes: Injection site reaction: Brief redness or mild soreness where the needle entered, usually resolving within hours