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Prepared solutions may be stored under refrigerated or frozen conditions as appropriate for the research protocol, with aliquoting commonly used to reduce repeated freeze-thaw cycles

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Investigators noted the relatively substantial placebo-associated weight loss as an important contextual factor when interpreting efficacy

Biotinidase Deficiency Profound biotinidase deficiency is an autosomal recessive disorder that is characterized by mutations in the BTD gene that result in enzyme activity that is less than 10% of the normal

[PMC free article: PMC11372654] [PubMed: 39226030] 367