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Besides microglial activation, disrupted autophagy process has been increasingly reported as a significant contributor to both chronic pain and AD (Yin et al., 2018)

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Interestingly, both hMSC-Ex-4 and wild-type hMSC treated with soluble Ex-4 exhibited elevated mRNA expression of GLP-1-R in a dose-dependent manner, suggesting a feedback mechanism that may potentiate hMSC responsiveness to Ex-4 [18]

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10.1016/j.amjms.2018.11.011 [DOI] [PubMed] [Google Scholar] 45.Dou X, Gao N, Yan D, Shan A

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