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10.1016/j.archoralbio.2019.03.012 171 XiaoJ.LuoC.LiA.CaiF.WangY.PanX.et al (2024)

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They help lower blood sugar by increasing insulin production and slowing the pace of food leaving the stomach

In type 1 diabetes, this mechanism is broken because the pancreas doesnt produce insulin

Demand for GLP-1 receptor agonists is expected to grow at an 11.7% CAGR between 2026 and 2036

In the intestinal L-cells, proglucagon is cleaved by the enzyme prohormone convertase 1/3 to produce GLP-1, along with other peptides including GLP-2 and glicentin