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Furthermore, it also induces the expression of mitochondrial transcription factor A (TFAM), a controller in replication and transcription of mitochondrial DNA, to further drive mitochondrial biogenesis (Jornayvaz and Shulman, 2010

Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: Reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse J Pharmacol Sci, 95 (1) (2004), pp

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For these reasons, GPx is especially significant in protecting of mitochondria against H 2 O 2 ,that are constantly generated during cell respiration [40, 41]

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