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The company also said that with higher doses, one in three patients achieved 20% weight loss in late-stage trials, while average weight loss has commonly been reported around 15% when combined with healthy diet and exercise

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It is essential to gain a deeper understanding of GIP safety to guide future research projects and develop GIP-based treatments [116]

If nausea, vomiting, or diarrhea remain significant at any dose, hold that dose for an additional two to four weeks before escalating