But, the amount of pain relief is often limited, and progress may stall for those with more severe or complex pain syndromes
Neuropharmacology 76, 175183
Russo RS, Gasperini S, Bubb G, Neuman L, Sloan LS, Diaz GA, et al
Common side effects include gastrointestinal discomfort, such as nausea and diarrhea
Some studies suggest that prolonged or excessive mTOR inhibition may impair muscle protein synthesis and potentially exacerbate sarcopenia in older adults, highlighting a possible trade-off between metabolic benefits and preservation of lean massan area requiring further investigation [28]
In G6PD-deficient infants in Saudi Arabia, where the Mediterranean variant predominates, an increased risk of severe infection and sepsis was seen in childhood, especially with catalase-positive organisms (38, 39)