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GLP-1 agonists bring about similar degrees of weight loss regardless of psychiatric status, but there are reasons to think obesity is different in patients with psychiatric disorders

Healthy fats: Avocado, olive oil, nuts, seeds, and oily fish such as salmon

Two medications we commonly discuss with patients are Mounjaro (Tirzepatide) and Ozempic

If considering a dose reduction for maintenance: Wait until weight has stabilized for at least 4 weeks at your current dose Reduce by one dose step (e.g., 12mg to 8mg), do not jump multiple steps Monitor weight closely for 8 weeks after the reduction If weight begins to increase, return to the previous maintenance dose The phase 3 trials specifically tested 4mg as a maintenance dose, suggesting Lilly sees viability in lower maintenance doses What happens if you stop Weight regain after discontinuing GLP-1 agonists is well documented with semaglutide and tirzepatide

Regular coolers work too

Regular exercise also helps boost GLP-1 and makes prescription GLP-1 medications more effective if you're taking them