Abstract Purpose of the Review Glucagon-like peptide 1 (GLP-1) receptor agonists (RA) have transformed obesity and type 2 diabetes (T2D) management
A qualified clinician can help determine which option is appropriate for a specific health situation
Their benefits extend beyond the improvement of impaired glucose and lipid metabolism, offering robust cardioprotection by counteracting pathological processes such as endothelial dysfunction, chronic inflammation, and cellular oxidative stress [5]
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Cannabis While no pre-clinical or mechanistic study has considered GLP-1RAs for cannabis misuse so far, a large epidemiological investigation has recently noted an association between semaglutide use and fewer cannabis-use disorders in both patients with T2DM ( N = 596,045) and patients with obesity ( N = 85,223) over a 1-year follow-up 114