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Unique properties associated with the brain penetrant iron chelator HBED reveal remarkable beneficial effects after brain trauma
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate
A Danish nationwide cohort study also reported a lower risk of corticosteroid use and hospitalization in IBD patients with DM2 undergoing GLP-1 RAs rather than other antidiabetic treatments (98)
What they found: Prevention of age-related changes in gene expression , NMN-treated mice had an expression profile closer to young mice Restoration of mitochondrial function in multiple tissues Improvement of insulin sensitivity of 35 to 50 % Preserved muscle strength and endurance Preserved bone density Better vision (NMN-treated mice had a slower decline in ophthalmologic parameters) No serious adverse effects Why it matters: This is the most ambitious preclinical study of NMN/NAD+ in animal aging models
10.1002/dmrr.1174 194 MonteiroK
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