glp 1 receptors in the brain JCI Current understanding and controversy on

10.1124/jpet.112.202010 J

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The transmembrane helices: Like any other G-protein coupled receptor, this protein has seven transmembrane helices (TM1-7) with surface exposed hydrophobic amino acids in the membrane region (see Figure 3b)

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"No, a loading protocol is not necessarily required," Gonzalez admits