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Clayton, S

76 In postmenopausal women, daily supplementation with melatonin, at a dose of 3 mg in the morning and 5 mg in the evening for a period of six months, significantly improved overall symptoms at four and six months compared with placebo in those with constipation-predominant IBS

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In addition to stimulating weight loss through these mechanisms, drugs like Ozempic and Wegovy may also improve obesity-related issues

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The most commonly reported side effects across GLP-1 medications are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation