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Diagrammatic Representation: A bidirectional arrow connects the gut and the brain

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For example, under hypoxic conditions, HIF-1 upregulates NANOG, OCT4, and SOX2 expression, promoting CSC survival and proliferation

Additionally, phytohormones such as ET, SA, JA, auxin, ABA, and cytokinins all affect leaf senescence (Lim et al., 2007)

Think of supplements as supporting your skin's foundation, whilst topical products handle the finishing touches