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Each component is studied for a different layer of the regenerative cycle: GHK-Cu for copper-mediated extracellular-matrix and collagen signaling, BPC-157 for angiogenic and growth-factor pathways, and TB-500 (acetylated Thymosin Beta-4) for actin-driven cell migration

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Co-administration of sermorelin with octreotide or lanreotide should be considered therapeutically contraindicated: the somatostatin analogue will predictably abolish the GH response to sermorelin