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Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models

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[PMC free article] [PubMed] [Google Scholar] Balercia G, Regoli F, Armeni T, Koverech A, Mantero F, Boscaro M.2005

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Alcohol also decreases glutathione production, the bodys natural defense mechanism, meaning NAPQI is more likely to build up in the liver in dangerous concentrations