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Survodutide, a glucagon/GLP-1 dual agonist, met its primary endpoint of histological improvement in MASH at 48 weeks and also demonstrated a statistically significant improvement in fibrosis, a secondary endpoint

You might notice saggy skin, dryness, wrinkles, and possibly some hair loss

This tension is also fueling debates about responsible prescribing and pharmaceutical advertising

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These drugs also are helpful for people with sleep apnea, which is associated with high blood pressure and increased cardiac risk

Retatrutide has shown common side effects similar to other GLP-1 receptor agonists, including: Nausea Vomiting Diarrohea Constipation Abdominal discomfort or bloating Some trial participants experienced a slight increase in resting heart rate, which has also been observed with other GLP-1 receptor agonists