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10.15252/embr.201643068 [DOI] [PMC free article] [PubMed] [Google Scholar] Andringa K.K., Coleman M.C., Aykin-Burns N., Hitchler M.J., Walsh S.A., Domann F.E., and Spitz D.R

Administered ipamorelin intravenously at 1, 10, and 100 mcg/kg to nine healthy adult men and measured GH, ACTH, cortisol, and prolactin over six hours [1]

The compound is endogenously released at sites of tissue injury through breakdown of SPARC and type I collagen meaning its biology connects directly to repair signaling rather than acting as an exogenous-only tool compound

This indirect approach helps overcome the challenges associated with absorbing intact Glutathione

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