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FASEB Journal

Exercise stimulates intestinal function and can help reduce constipation

10.1016/j.lfs.2020.118889 Life Sci

The phase 1b combination study by Enebo and colleagues, which examined multiple ascending doses of cagrilintide together with semaglutide 2.4 mg, characterized pharmacodynamic markers including appetite and gastrointestinal effects during the early weeks of dosing, before meaningful body-weight separation had emerged

0.3 ml aliquots of the supernatant, 0.75 ml of 150 mM phosphate buffer (pH 7.4) containing 5 mM EDTA, and 0.15 ml of 10 mM DTT were added to determine total ascorbate

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