Nausea affects up to 20% of semaglutide users and is the most common reason people discontinue treatment (Alhazmi & le Roux 2026, Frontiers in Endocrinology)
This raises the question of whether mitochondrial dysfunction could be a factor that causes the disease to progress
In the liver, it offers antioxidant support for liver tissue protection and promotes p450 phase II conjugation pathways to support detoxification
Jinek, M
Summary Keywords mitochondria, -oxidation, carnitine, kidney, CPT Citation Console L, Scalise M, Giangregorio N, Tonazzi A, Barile M and Indiveri C (2020) The Link Between the Mitochondrial Fatty Acid Oxidation Derangement and Kidney Injury
However, the precise role of CD26 in T cells and other immune cells as well as the precise signaling pathway involved have not as yet been elucidated