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Various types of cells, including osteoclasts, osteoblasts, and osteocytes, maintain the bone, and intercellular communication between these cells is facilitated by hormones and cytokines, the nervous system, and cell-to-cell adhesion

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doi: 10.1210/endrev/bnz009 5 MussoGCassaderMRosinaFGambinoR

We also show that both TAM injection and TAM chow paradigms have inherent, although different, effects on adult neurogenesis, underscoring the need to compare TAM-treated experimental animals to genetic controls similarly treated with TAM, regardless of route of administration

Taking high doses for extended periods may signal your body to slow down its own production