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Results showed average weight reductions of 16.0% on 5 mg, 21.4% on 10 mg, and 22.5% on 15 mg over 72 weeks

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The surface topography deduced from AFM along with the hight and porosity of the nanoparticles (NPs)

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These methods involve the use of mitochondrially-targeted compounds (e.g., oligomycin, FCCP) in conjunction with the measurement of oxygen consumption rate to assess mitochondrial respiration parameters (Seahorse XFp analyzer technology) [39, 62, 63], as well as high-resolution respirometry to evaluate mitochondrial oxidative phosphorylation (OXPHOS) capacity with complex I + II-linked substrates (Oroboros O2k-technology) [42]