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Elevated GGT expression can indicate the early-stage risk of tumor development, as suggested by an epidemiological study linking high GGT expression with increased risk of prostate cancer development (145)

However, the most important difference was observed for carnitine and its derivatives acetylcarnitine and propionylcarnitine, which were substantially reduced in cKOt, while creatinine was increased (Figure 3, K and L)

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This suggests that antibiotics attenuate the SREBP2 response to a low-cholesterol state by eliminating the positive effect of gut microbiota-mediated lipid-lowering action of atorvastatin