Maquart 1988 J Clin Invest showed that GHK-Cu at nanomolar concentration stimulates type I collagen synthesis by fibroblasts by 60-200 %, of glycosaminoglycans (hyaluronic acid, heparan sulphate) and proteoglycans
This variant has been developed particularly for evaluation in cell growth studies
Thus, deficiency in both growth hormone and estrogen is associated with increased serum concentrations of CRP, IL-6, and TNF-
A.et al (1996)
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Glyoxylase is similar, also generating a transient intermediate adduct between its substrate, methyl glyoxal, and glutathione