Evidence is insufficient for weight loss (failed Phase 2b trial) and preliminary for osteoarthritis (small open-label studies without adequate controls)
While there are no definitive studies indicating adverse interactions, it is essential to consult with a healthcare provider before combining these substances
doi: 10.3389/fphar.2025.1638527 Received 30 May 2025 Accepted 16 July 2025 Published 05 August 2025 Volume 16 - 2025 Edited by Di Yuan, Xidian University, China Reviewed by Asmaa ShamsEldeen, Cairo University, Egypt Jinmei Tuo, Zunyi Medical University, China Rao Chaolong, Chengdu University of Traditional Chinese Medicine, China Updates Copyright 2025 Alolayan and Alhowail
Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse
Excessive vitamin C intake can lead to serious adverse effects, including iron accumulation in the body and the formation of kidney stones
A possible mechanism explaining this is that a plant-based diet low in certain proteins may elevate the levels of Parkin and the protective PINK1 kinase
