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The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer

In phases I and II, the xenobiotic is transformed into a more soluble and less toxic product and, in phase III, are transported for cellular excretion

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New insights into the role of oxidative stress mechanisms in pathophysiology and treatment of multiple sclerosis