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However, the therapy requires lifelong commitment and regular monitoring to ensure the dose remains appropriate over time, as the bodys thyroid hormone requirements may change due to aging, weight changes, pregnancy, or other health conditions

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Researchers concerned about off-target effects should review the mechanistic literature before finalising endpoint selection

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In preclinical studies with rats, dulaglutide, the active ingredient in Trulicity, led to an increased incidence of these tumors

Compounded: Wegovy and Zepbound are FDA-approved medications that underwent FDA review for safety, effectiveness, and manufacturing quality