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They are often made in unregulated environments , with no hygiene standards or safety checks

Ishikawa, H., Ma, Z

In a recent paper, it was shown that RBCs can serve as biomarkers of the aging process: important RBC indices, e.g., the erythrocyte hemoglobin concentration, the mean corpuscular volume (MCV), and erythrocyte metabolism change with the age of the individuals [418]

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doi: 10.1016/j.jconrel.2024.10.062 8 Moreno-YruelaCFierzB

Sublingual dissolving microneedle (SLDMN)-based vaccine for inducing mucosal immunity against SARS-CoV-2