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For weekly formulations like semaglutide and tirzepatide, the peak plasma concentration arrives 1 to 3 days after injection

This is known as oxidative stress an imbalance between the production of ROS and their neutralisation by antioxidants

Cole IS & Smirnoff N (2020) Unravelling the Function of the Unusual Antioxidant Ergothioneine in Plants and Photosynthetic Protists

Direct glutathione supplementation: An RCT in India randomized 206 people with type 2 diabetes (aged 31-78, HbA1c 7.1-9.7%) to receive either 500 mg glutathione daily alongside antidiabetic medications for 6 months, or antidiabetic medications alone

It helps to reduce oxidative stress and inflammation, which are key factors in the development of heart disease