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Oxytocin, known as the bonding hormone, is used off-label in men to enhance mood, touch sensitivity, and orgasmic response
Once someone goes off a GLP-1, most peoples weight goes back to its baseline after three years
This structural advantage has made peptides central to modern longevity and geroscience research programs focused on biological health outcomes
Zittoun J, Farcet JP, Marquet J, Sultan C, Zittoun R
Regulation of basal tone, relaxation and contraction of the lower oesophageal sphincter
Important safety considerations include: Risk of acute pancreatitis: urgent medical review needed for severe, persistent abdominal pain (with or without back pain) Gallbladder disorders: seek medical advice for symptoms of gallstones (right upper abdominal pain, nausea) Diabetic retinopathy complications: particularly with semaglutide in those with pre-existing retinopathy Hypoglycaemia: risk is low unless combined with insulin or sulfonylureas, which may require dose adjustment Reports of mood changes and suicidal ideation in patients taking GLP-1 receptor agonists are being monitored by regulatory authorities
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