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112 Chronic inflammation in the TME, which is mediated by cytokines such as IL-6, IL-8, and TNF-, can drive epigenetic and transcriptional reprogramming via the NF-B, JAK/STAT, and COX-2 pathways

doi:10.1080/02763869.2019.1588072 18

(2023, June 26)

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Conversely, constipation may also emerge, often exacerbated by dietary habits