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In HNSCC cell lines, foretinib alone strongly inhibited cell growth (cell IC50 0.610.79 M) and exhibited synergistic inhibition of cell proliferation when combined with the EGFR inhibitor erlotinib [117]

Use in pregnancy is not recommended unless the potential benefit justifies the potential risk to the fetus

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Use caution if you have autoimmune disease, cancer history, endocrine disorders, or are taking immunomodulators, sedatives, or sleep medications

Additionally, the B-vitamins folate, vitamin B 12 , and vitamin B 6 work together to maintain normal concentrations of homocysteine

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