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For example, estrogen signaling has been shown to enhance the anorexigenic effects of GLP-1 RAs by modulating central pathways involved in food reward, which could account for the more pronounced weight loss observed in premenopausal women [49, 50]

Mallory Fox, a personal trainer based in Scottsdale, Arizona, said she's had many prospective clients ask about whether she works with people taking GLP-1s, to the point where she's considered developing an online program for those on the medications

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Morning dosing also aligns with the body natural cortisol rhythm

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